Meltzer’s Triad

Meltzer Triad

Meltzer’s triad describes the classical symptoms suggesting the diagnosis of cryoglobulinaemia of polyclonal CGs seen in essential-, viral-, or connective tissue disease-associated cryoglobulinaemia. The triad consists of: palpable purpura arthralgia (joint pain) weakness. Do note that Meltzer’s triad typically occurs in Type 2 and Type 3 Cryoglobulinemia ie Mixed Cryoglobulinemia. The classic presentation of mixed (types II and III) cryoglobulinaemia is characterized …

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