Cherry Red Spot : Easy Mnemonic to Remember Causes

What is cherry-red spot?

Cherry-red spot at the macula is a clinical sign seen in the context of
thickening and loss of transparency of the retina at the posterior pole. The
fovea being the thinnest part of the retina and devoid of ganglion cells, retains
relative transparency, due to which the color of the choroids shines through.
In case of lipid storage diseases, the lipids are stored in the ganglion cell
layer of the retina, giving the retina a white appearance. As ganglion cells
are absent at the foveola, this area retains relative transparency and
contrasts with the surrounding retina

What are the causes of cherry-red spot?

i. CRAO Central Retinal Artery Occlusion
ii. Sphingolipidoses like Gaucher’s disease, Neimann-Pick disease, Tay-
Sachs disease, Goldberg syndrome, Faber syndrome, gangliosidosis
GM1-type 2, Sandoff’s disease
iii. Berlin edema/commotio retinae
iv. Macular retinal hole with surrounding retinal detachment
v. Quinine toxicity
vi. Hollenhorst syndrome (chorioretinal artery infarction syndrome)
vii. Cardiac myxomas
viii. Severe hypertension
ix. Temporal arteritis
x. Myotonic dystrophy syndrome.

Mnemonics of Ophthalmology


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