Loop diuretics represent a sub-category of diuretic drugs that act at the ascending tract of the loop of Henle, the anatomical element of the nephron. They are used for the treatment of hypertension and edema often caused by heart failure and renal failure.
The loop diuretics act on the Na-K-Cl (membrane co-carrier protein) cotransporter in the ascending tract of the loop of Henle and inhibit the reabsorption of sodium and chlorine.
We have some super useful mnemonics to remember the properties of Loop diuretics.
Loop diuretics Classification: remember “E.T. is FABulous”
Clinical uses of Loop diuretics include: remember “he he”
Side effects of Loop diuretics include: remember the mnemonic “HypO”
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