Pharmacological inhibition of gastric acid secretion is achieved most effectively with proton pump inhibitors (PPIs), more correctly referred to as hydrogen-potassium ATPase inhibitors.
Proton Pump Inhibitors examples (remember OLPER’s milk):
Medical uses of Proton Pump Inhibitors imclude ( remember PhD & GERD):
Peptic ulcer disease including NSAID associated ulcers
Helicobacter pylori eradication therapy
Gastroesophageal reflux disease (GERD)
In general, proton pump inhibitors are well tolerated, and the incidence of short-term adverse effects is relatively low. The range and occurrence of adverse effects are similar for all of the PPIs, though they have been reported more frequently with omeprazole.
Gastric acid is important for breakdown of food and release of micronutrients, and some studies have shown possibilities for interference with absorption of
(remember Roman numerals IVCM)
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