Rate limiting enzymes are one of the most frequently encountered Biochemistry one-liners or direct MCQs in NEET-PG and other PG entrance exams.
Rate limiting enzymes are also an important topic for medical school exams.
You must know the rate limiting enzymes of all the important biochemical reactions as well as the substrate and product for that step.
Use this list for a rapid revision of all Rate limiting enzymes.
|SR NUM||METABOLIC REACTION||RATE LIMITING ENZYMES|
|5||Fatty acid synthesis||Acetyl CoA carboxylase|
|6||Cholestrol synthesis||HMG CoA reductase|
|7||Bile acid synthesis||7-alpha- hydroxylase|
|8||Urea synthesis||carbonyl phosphate synthetase, ornithine transcarbonylase|
|9||porphyrin synthesis||D- aminolevulinate synthetase|
|10||Uric acid synthesis||Xanthine oxidase|
|11||Purine biosynthesis||Phosphoribosyl prophosphate synthetase|
|12||HMP shunt||Glucose-6-Phosphate dehydrogenase|
|13||TCA cycle||Isocitrate dehydrogenase|
|14||Fatty acid oxidation||Carnitine acyltransferase-1|
That list seems complete, doesn’t it ?
Do let us know in the comments below, if we missed any reaction and its rate limiting enzyme.
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